HuagongsheHuagongshe Chemistry Print Report · For research reference only
Thionyl Chloride → HCID 14622462, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Thionyl Chloride | HCID 24386 | — |
| Reactant | (6,7-Dimethoxyisoquinolin-1-yl)methanol | HCID 14622433 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 14622462 | HCID 14622462 | 147.6% |
Reaction Steps
To 306.3 mg of 6, 7-dimethoxyisoquinolin-1-ylmethanol (1.397 mmol) were added 20 ml of dry CH2Cl2 and 665 mg of thionyl chloride (5.95 mmol) and the mixture was stirred for 2 hours at room temperature. The reaction solution was concentrated to give 490mg of 1-chloro-(6,7-dimethoxyisoquinolin-1-yl)methane (III-1) as brown crystals.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04882338 |
| Source dataset | uspto-grants-1989_11 |
| ORD ID | ord-5ab8c4bc1dbe40f58d3fc486404e70b4 |
| Source note | uspto-grants-1989_11 |