Water → 4-Chloro-1-(4-chloro-2-methylphenoxy)-2-butanol

HRID 1639055Notes

Reaction equation

HRID 1639055 reaction equation
[CH3:1][C:2]1[CH:7]=[C:6]([Cl:8])[CH:5]=[CH:4][C:3]=1[OH:9].Cl[CH2:11][CH:12]([OH:16])[CH2:13][CH2:14][Cl:15].[OH-].[Na+].O>C(O)(C)(C)C>[Cl:15][CH2:14][CH2:13][CH:12]([OH:16])[CH2:11][O:9][C:3]1[CH:4]=[CH:5][C:6]([Cl:8])=[CH:7][C:2]=1[CH3:1]

Participants

6

Reactant 4

HCID 962WaterHCID 14798Sodium HydroxideHCID 148554-Chloro-2-methylphenolHCID 170211,4-Dichloro-2-butanol

Product 1

HCID 131203464-Chloro-1-(4-chloro-2-methylphenoxy)-2-butanol

Reagents, catalysts & solvents 1

HCID 6386tert-ButanolSolvent

Procedure

4-Chloro-1(4-chloro-2-methylphenoxy)-2-butanol was prepared according to the procedure of Preparation 4 using 105 g (0.74 mole) of 2-methyl-4-chlorophenol, 171.5 g (1.2 mole) of 1,4-dichloro-2-butanol, 50.3 g of sodium hydroxide, 300 ml of water and 300 ml of tertiary butanol. There was obtained 84 g (45.5%) of product which distilled at 135° C./0.01 mm.

Sources & evidence

ORD record
ord-c789af98f46a43a09a400769663f3d53
Source dataset
uspto-grants-1989_11
Patent number
US04882330

Reaction notes

Loading…