HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-(3-(Trifluoromethyl)phenyl)piperazine → HCID 14422844, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-(3-(Trifluoromethyl)phenyl)piperazine | HCID 4296 | — |
| Reactant | Sodium Carbonate | HCID 10340 | — |
| Reactant | 4-Chloro1-phenoxy-2-butanol | HCID 13120342 | — |
| Solvent | 1-Butanol | HCID 263 | — |
| Product | HCID 14422844 | HCID 14422844 | 66% |
Reaction Steps
This compound was prepared according to the procedure of Example 6. A mixture of 3.5 g (0.015 mole) of N-(α, α, αtrifluoro-m-tolyl)piperazine, 3.0 g (0.015 mole) of 4-chloro1-phenoxy-2-butanol and 5.3 g (0.05 mole) of anhydrous sodium carbonate in 100 ml of 1-butanol gave 3.9 g (66%) of white powder, m.p. 83°-84° C. The recrystallizing solvent used in isopropyl alcohol.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04882330 |
| Source dataset | uspto-grants-1989_11 |
| ORD ID | ord-856ddb7d74d34434808ecd72af5863cc |
| Source note | uspto-grants-1989_11 |