Potassium Iodide → HCID 15631760, compound

Participants

Reaction Steps

This compound was prepared according to the procedure used to synthesize the compound of Example 6. A mixture of 3.3 g (0.02 mole) of 1-(2-pyridyl)piperazine, 5.4 g (0.02 mole) of 4-chloro-1-(3-trifluoromethylphenoxy)-2-butanol, 6.4 g (0.06 mole) of anhydrous sodium carbonate and 0.4 g of potassium iodide in 100 ml of 1-butanol gave 2.8 g (35%) of the title compound as an off-white solid, m.p. 81°-81.5° C. Recrystallizing solvent used was isopropyl ether.

Provenance & Evidence