Ammonia → HCID 19840378, compound

Participants

Reaction Steps

3.7 g. of the 5-(2-cyanopropan-2-yl)-2-(4-pyridinyl)benzimidazole (prepared in Example 15) are stirred for 3 hours at 50° C. in 40 ml. 80% sulphuric acid, the compound thereby slowly going into solution. The reaction mixture is then poured on to ice, rendered alkaline with ammonia, filtered off with suction and recrystallised from ethanol. There are obtained 2.4 g. (61% of theory) of the title compound in the form of colourless crystals; m.p. 274°-276° C.

Provenance & Evidence