Hydrochloric Acid → HCID 19840340, compound

Participants

Reaction Steps

2.4 g. 5-(2-acetamidomethylpropan-2-yl)-2-methylbenzimidazole (prepared in Example 29) are boiled under reflux for 24 hours in 60 ml. ethanol and 60 ml. concentrated hydrochloric acid. The solvent is then removed in a vacuum, the residue is neutralised with 2N aqueous ammonia solution and the organic phase is dried over anhydrous sodium sulphate. After filtration and evaporation, there is obtained 0.87 g. of the title compound in the form of an oil.

Provenance & Evidence