3-Chloropropionyl chloride → HCID 19839192, compound

Participants

Reaction Steps

To a solution of 45 g. (0.5 moles) of methyl carbazate in 375 ml. of acetonitrile 63.5 g. (0.5 moles) of 3-chloro-propionyl chloride are added dropwise. The reaction mixture is heated to boiling for 16 hours, clarified and cooled. The precipitated crystals are filtered. Thus 70.5 g. of the desired compound are obtained in the form of white crystals. Yield: 78.3%. M.p.: 129° C.

Provenance & Evidence