2-Chloroethanol → HCID 19839331, compound

Participants

Reaction Steps

Initially a hydroxyethyl quat was made by reacting 100 grams of dioctyl methyl amine with 42 mLs of 2-chloroethanol in 200 grams of methylethyl ketone solvent at reflux for 5 hours to obtain a methylethyl ketone solution of dioctyl methyl hydroxyethyl ammonium chloride. To this was added dropwise, 59.04 grams of glutaryl dichloride over a 1 hour period while sparging the mixture with nitrogen. This was held at reflux (90° C.) for 30 minutes to give a brown solution of di(dioctyl methyl ammonium ethyl)glutarate dichloride which could be recovered by evaporation of the methylethyl ketone under vacuum.

Provenance & Evidence