反应详情

温度

80 °C

75 mg (0.26 mmol) of 4-(2-fluoro-4-nitrophenoxy)-3-methyl-1H-indazole (from example II) are dissolved in 3 ml of ethanol, and 261 mg (5.22 mmol) of hydrazine hydrate and 10 mg of 10% palladium on activated carbon are added. The mixture is heated at 80° C. for two hours and then filtered through kieselguhr. The filtrate is concentrated under reduced pressure.

1. filtrationfiltered through kieselguhr
2. concentrationThe filtrate is concentrated under reduced pressure