HuagongsheHuagongshe Chemistry Print Report · For research reference only
Potassium Carbonate → 4-(2-Fluoro-4-nitrophenoxy)-1,2-benzisoxazole-3-amine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | 1,2-Difluoro-4-nitrobenzene | HCID 123053 | — |
| Reactant | 3-Aminobenzo[d]isoxazol-4-ol | HCID 135703705 | — |
| Solvent | Water | HCID 962 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | 4-(2-Fluoro-4-nitrophenoxy)-1,2-benzisoxazole-3-amine | HCID 17979276 | — |
Reaction Steps
94.37 mg (0.63 mmol) of 3-amino-1,2-benzisoxazol-4-ol (from example V), 100 mg (0.63 mmol) of 3,4-difluoronitrobenzene and 95.56 mg (0.69 mmol) of potassium carbonate are suspended in 3 ml of anhydrous dimethylformamide and stirred at room temperature for 16 hours. The reaction solution is then diluted with water, and the precipitate is filtered off. The product is dried under high vacuum.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07737153B2 |
| Source dataset | uspto-grants-2010_06 |
| ORD ID | ord-dc5d146c38a84b3dac59f0da5117b260 |
| Source note | uspto-grants-2010_06 |