Dimethylformamide → tert-butyl N-[4-[2-(1-azabicyclo[2.2.2]octan-3-yloxy)pyrimidin-5-yl]-2-nitrophenyl]carbamate
Reaction equation
[Br:1][c:2]1[cH:3][n:4][c:5]([O:8][CH:9]2[CH2:10][N:11]3[CH2:12][CH2:13][CH:14]2[CH2:15][CH2:16]3)[n:6][cH:7]1.[C:17]([CH3:18])([CH3:19])([CH3:20])[O:21][C:22]([NH:23][c:24]1[c:25]([N+:39](=[O:40])[O-:41])[cH:26][c:27]([B:30]2[O:31][C:32]([CH3:33])([CH3:34])[C:35]([CH3:36])([CH3:37])[O:38]2)[cH:28][cH:29]1)=[O:42].[O:43]1[CH2:44][CH2:45][O:46][CH2:47][CH2:48]1.[O:49]=[CH:50][N:51]([CH3:52])[CH3:53].[O:56]=[C:57]([CH:58]=[CH:59][c:60]1[cH:61][cH:62][cH:63][cH:64][cH:65]1)[CH:66]=[CH:67][c:68]1[cH:69][cH:70][cH:71][cH:72][cH:73]1.[O:74]=[C:75]([CH:76]=[CH:77][c:78]1[cH:79][cH:80][cH:81][cH:82][cH:83]1)[CH:84]=[CH:85][c:86]1[cH:87][cH:88][cH:89][cH:90][cH:91]1.[O:92]=[C:93]([CH:94]=[CH:95][c:96]1[cH:97][cH:98][cH:99][cH:100][cH:101]1)[CH:102]=[CH:103][c:104]1[cH:105][cH:106][cH:107][cH:108][cH:109]1.[Pd:54].[Pd:55]>>[c:2]1(-[c:27]2[cH:26][c:25]([N+:39](=[O:40])[O-:41])[c:24]([NH:23][C:22]([O:21][C:17]([CH3:18])([CH3:19])[CH3:20])=[O:42])[cH:29][cH:28]2)[cH:3][n:4][c:5]([O:8][CH:9]2[CH2:10][N:11]3[CH2:12][CH2:13][CH:14]2[CH2:15][CH2:16]3)[n:6][cH:7]1Participants
7
Reactant 6
Product 1
Sources & evidence
- ORD record
- ord-1207797b7aeb42879b0139c19d40ccb3
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (9/10)
Reaction notes
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