HuagongsheHuagongshe Chemistry Print Report · For research reference only
Diethyl (ethoxymethylene)malonate → 2-((4-Methoxy-phenylamino)-methylene)-malonic acid diethyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Diethyl (ethoxymethylene)malonate | HCID 6871 | — |
| Reactant | P-Anisidine | HCID 7732 | — |
| Product | 2-((4-Methoxy-phenylamino)-methylene)-malonic acid diethyl ester | HCID 618981 | — |
Reaction Steps
A mixture of 4methoxyaniline (28.3 g, 0.230 mol) in diethyl ethoxymethylene-malonate (46.0 mL, 0.230 mol) was allowed to stir at rt for 16 h. Removal of solvent gave diethyl ([(4-methoxyphenyl)aniino]methylenelmalonate. LCMS: (FA) ES+ 294.2.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08110687B2 |
| Source dataset | uspto-grants-2012_02 |
| ORD ID | ord-a209f72593a3414c9a6d0bff813919ae |
| Source note | uspto-grants-2012_02 |