Dichloromethane → 4-(4-BOC-piperazinosulfonyl)bromobenzene

HRID 164020Notes

Reaction equation

HRID 164020 reaction equation
[Br:10][c:11]1[cH:12][cH:13][c:14]([S:17](=[O:18])(=[O:19])[Cl:20])[cH:15][cH:16]1.[C:21]([CH3:22])([CH3:23])([CH3:24])[O:25][C:26](=[O:27])[N:28]1[CH2:29][CH2:30][NH:31][CH2:32][CH2:33]1.[CH2:34]([Cl:35])[Cl:36].[CH:1]([N:2]([CH:3]([CH3:4])[CH3:5])[CH2:6][CH3:7])([CH3:8])[CH3:9]>>[Br:10][c:11]1[cH:12][cH:13][c:14]([S:17](=[O:18])(=[O:19])[N:31]2[CH2:30][CH2:29][N:28]([C:26]([O:25][C:21]([CH3:22])([CH3:23])[CH3:24])=[O:27])[CH2:33][CH2:32]2)[cH:15][cH:16]1

Participants

5

Reactant 4

HCID 6344DichloromethaneHCID 7396p-Bromobenzenesulfonyl chlorideHCID 81531DiisopropylethylamineHCID 143452tert-Butyl piperazine-1-carboxylate

Product 1

HCID 166655764-(4-BOC-piperazinosulfonyl)bromobenzene

Sources & evidence

ORD record
ord-091067b67185481984089970208dcf2a
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Reaction notes

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