反应详情

2.2 g (9.4 mmol) 2,2,2-trifluoroethyltrifluoromethanesulphonate were added to 2.0 g (18.7 mmol) benzylamine in 50 mL xylene and the reaction mixture was refluxed overnight. After cooling the precipitate formed was suction filtered, washed with DIPE and the filtrate was evaporated down using the rotary evaporator. The residue was purified by flash chromatography. The product fractions were combined and evaporated down i.vac.

1. temperaturethe reaction mixture was refluxed overnight
2. temperatureAfter cooling the precipitate
3. customformed
4. filtrationfiltered
5. washwashed with DIPE
6. customthe filtrate was evaporated down
7. customthe rotary evaporator
8. customThe residue was purified by flash chromatography
9. customevaporated down i.vac