Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1640370Generated: October 31, 2026

Acetic Anhydride → HCID 86615839, compound

https://huagongshe.com/reaction/1640370

Reaction equation

Participants

RoleNameHCIDCharge
ReactantAcetic AnhydrideHCID 7918—
ReactantMaleic AnhydrideHCID 7923—
ReactantPropargylamineHCID 239041—
ReactantSodium AcetateHCID 517045—
ProductHCID 86615839HCID 86615839—

Reaction Steps

After the reaction of propargylamine and maleic anhydride in the presence of TEA, the intermediate acid was cyclized in the presence of acetic anhydride and sodium acetate at 70° C., to afford the desired propargylamine maleimide.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08114636B2
Source datasetuspto-grants-2012_02
ORD IDord-bee88a837a4948e98f72d634eb18a00c
Source noteuspto-grants-2012_02