Dichloromethane → 4-Chloro-7-[3-(2,5-dioxoimidazolidin-1-yl)propoxy]-6-methoxyquinazoline
Reaction equation
[Cl:1][c:2]1[n:3][cH:4][n:5][c:6]2[cH:7][c:8]([OH:14])[c:9]([O:12][CH3:13])[cH:10][c:11]12.[Cl:59][CH2:60][Cl:61].[O:45]=[C:46]([O:47][CH:48]([CH3:49])[CH3:50])[N:51]=[N:52][C:53]([O:54][CH:55]([CH3:56])[CH3:57])=[O:58].[OH:15][CH2:16][CH2:17][CH2:18][N:19]1[C:20](=[O:25])[NH:21][CH2:22][C:23]1=[O:24].[c:26]1([P:27]([c:28]2[cH:29][cH:30][cH:31][cH:32][cH:33]2)[c:34]2[cH:35][cH:36][cH:37][cH:38][cH:39]2)[cH:40][cH:41][cH:42][cH:43][cH:44]1>>[Cl:1][c:2]1[n:3][cH:4][n:5][c:6]2[cH:7][c:8]([O:14][CH2:16][CH2:17][CH2:18][N:19]3[C:20](=[O:25])[NH:21][CH2:22][C:23]3=[O:24])[c:9]([O:12][CH3:13])[cH:10][c:11]12Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-d9197dea133146cbbf5bf1673e9386ab
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (9/10)
Reaction notes
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