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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1640439Generated: October 27, 2026

Furfurylamine → N4-((furan-2-yl)methyl)-N6-(5-methyl-1H-pyrazol-3-yl)-2-styrylpyrimidine-4,6-diamine

https://huagongshe.com/reaction/1640439

Reaction equation

Participants

RoleNameHCIDCharge
ReactantFurfurylamineHCID 3438—
Reactant3-(4-Methoxyphenyl)prop-2-enenitrileHCID 34240—
Reactant1H-Pyrazol-3-amine, 5-methyl-HCID 93146—
ProductN4-((furan-2-yl)methyl)-N6-(5-methyl-1H-pyrazol-3-yl)-2-styrylpyrimidine-4,6-diamineHCID 86613127—

Reaction Steps

Example 162 was synthesized via Scheme 6 according to the general scheme provided above with the appropriate starting materials 3-(4-methoxyphenyl)acrylonitrile, 5-methyl-1H-pyrazole-3-amine, and (furan-2-yl)methanamine. Structure of the target was confirmed by 1H-NMR. The 1H-NMR is attached.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08114870B2
Source datasetuspto-grants-2012_02
ORD IDord-277a480dda3c4dd49d931db364614aad
Source noteuspto-grants-2012_02