Methylamine → HCID 66737716, compound

HRID 1640530Notes

Reaction equation

HRID 1640530 reaction equation
[CH3:1][NH2:2].[CH3:3][O:4][C:5]1[CH:6]=[N:7][C:8]2[CH:9]=[CH:10][CH:11]=[C:12]([CH:15]=O)[C:13]=2[N:14]=1>>[CH3:3][O:4][C:5]1[CH:6]=[N:7][C:8]2[C:13]([N:14]=1)=[C:12]([CH2:15][NH:2][CH3:1])[CH:11]=[CH:10][CH:9]=2

Participants

3

Reactant 2

HCID 6329MethylamineHCID 716074383-Methoxyquinoxaline-5-carbaldehyde

Product 1

HCID 66737716HCID 66737716, compound

Procedure

Methylamine (2M in THF, 5 mL) and 3-methoxy-quinoxaline-5-carbaldehyde (0.94 g, 5 mmol, prepared according to WO 2006/021448) were coupled according to method K. The title amine was isolated as a yellowish solid (0.52 g, 51% yield).

Sources & evidence

ORD record
ord-9a0793d869514e77bdd00ffc73b1915e
Source dataset
uspto-grants-2012_02
Patent number
US08114867B2

Reaction notes

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