HCID 66738037, compound → HCID 86641876, compound

HRID 1640915Notes

Reaction equation

HRID 1640915 reaction equation
[N:1]([CH:4]([C:6]1[CH:7]=[CH:8][C:9](F)=[N:10][CH:11]=1)[CH3:5])=[N+:2]=[N-:3].[S:13]1[CH:17]=[CH:16][C:15]2[CH:18]=[CH:19][CH:20]=[C:21](C3C=CN=CC=3C(O)C)[C:14]1=2>>[N:1]([CH:4]([C:6]1[CH:11]=[N:10][CH:9]=[CH:8][C:7]=1[C:21]1[C:14]2[S:13][CH:17]=[CH:16][C:15]=2[CH:18]=[CH:19][CH:20]=1)[CH3:5])=[N+:2]=[N-:3]

Participants

3

Reactant 2

HCID 66738037HCID 66738037, compoundHCID 866404925-(1-Azidoethyl)-2-fluoropyridine

Product 1

HCID 86641876HCID 86641876, compound

Procedure

Using a procedure similar to the one used for 5-(1-azido-ethyl)-2-fluoro-pyridine above, prepare the title intermediate from 1-(4-(benzo[b]thiophen-7-yl)pyridin-3-yl)ethanol as a brown oil (0.66 g, 93%). MS (ES) m/z 280 [M+1]+.

Sources & evidence

ORD record
ord-094fe00a18fb420db701739b9aed1970
Source dataset
uspto-grants-2012_02
Patent number
US08114872B2

Reaction notes

Loading…