Trityl chloride → HCID 86643840, compound

Participants

Reaction Steps

2,2,2-Trifluoro-N-[5-(3-fluoro-benzenesulfonyl)-1H-indazol-3-yl]-acetamide, (17.93 g, 46.33 mmol) in dry dichloromethane (300 mL) was treated with chlorotriphenylmethane (14.22 g, 50.96 mmol) and triethylamine (14.2 mL, 102 mmol). After stirring at room temperature for two days, the reaction was washed with a solution of NH4Cl, dried and evaporated. The crude was used as such in the next step without any further purification.

Provenance & Evidence