反应详情

Under argon, 150 mg (0.55 mmol) of 4-(2-fluoro-4-nitrophenoxy)-1-benzofuran (from example XXII) are initially charged in 5 ml of ethanol/tetrahydrofuran (1:1), platinum(IV) oxide is added and the mixture is hydrogenated under atmospheric pressure for 2 hours. The suspension is filtered off through CELITE (diatomaceous earth), the filtercake is washed with ethanol and the filtrate is concentrated using a rotary evaporator.

1. filtrationThe suspension is filtered off through CELITE (diatomaceous earth)
2. washthe filtercake is washed with ethanol
3. concentrationthe filtrate is concentrated
4. customa rotary evaporator