1-Acetylpiperazine → HCID 59553079, compound

Participants

Reaction Steps

Compound is prepared from N-[4-(2-chloroethoxy)-naphthalen-1-yl]-3-fluoro-5-piperidin-1-yl-benzamide and 4-acetylpiperizine according to conditions described in general procedure N. 1H NMR 300 MHz (CDCl3) 8.3(dd, 1H, J=1.8 and 8.7 Hz), 7.9(s, 1H), 7.84(d, 1H, J=7.5 Hz), 7.74(d, 1H, J=8.7 Hz), 7.54(m, 2H), 7.31(s, 1H), 6.99(d, 1H, J=7.5 Hz), 6.84(d, 1H, J=8.1 Hz), 6.76(d, 1H, J=11.7 Hz), 4.32(t, 2H, J=5.7 Hz), 3.66(t, 2H, J=5.4), 3.5(t, 2H, J=5.4 Hz), 3.28(m, 4H), 3.0 (t, 2H, J=5.7 Hz), 2.65(m, 4H), 2.05(s, 3H), 1.62-1.8(m, 6H).

Provenance & Evidence