HuagongsheHuagongshe Chemistry Print Report · For research reference only
Potassium Carbonate → HCID 66737812, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | Piperonylamine | HCID 2723901 | — |
| Reactant | 1-(BroMoMethyl)-3-isopropoxybenzene | HCID 21714701 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | HCID 66737812 | HCID 66737812 | — |
Reaction Steps
A mixture of 4-piperidone hydrochloride monohydrate (19.52 g, 127.12 mmol), 1-Bromomethyl-3-isopropoxy-benzene (19.41 g, 84.76 mmol) and K2CO3 in DMF (150 mL) is stirred at rt for 16 hr. Solvent is removed in vacco, the residue is extract (EtOAc/Brine), dried (Na2SO4), concentrated, and purified by chromatography (silica gel, EtoAc/hexanes, 2/3) to afford 14-4. (MH+, 266)
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08114887B2 |
| Source dataset | uspto-grants-2012_02 |
| ORD ID | ord-deabc23b72914a80ae3d76a7c39ac737 |
| Source note | uspto-grants-2012_02 |