Piperidine, 1-(2-chloroethyl)-, hydrochloride → HCID 23729164, compound

Participants

Reaction Steps

The title compound was prepared from 4-(3,5-dimethyl-pyrazol-1-yl)-phenol (0.1 g, 0.53 mmol), 1-(2-chloroethyl)piperidine hydrochloride (0.2 g, 1.1 mmol) using the general procedure C with a yield of 44% (70 mg); 1H NMR (400 MHz, CDCl3) 7.30 (d, J=8.8 Hz, 2H), 6.95 (d, J=8.8 Hz, 2H), 5.96 (s, 1H), 4.14 (t, J=12, 6 Hz, 2H), 2.78 (t, J=12, 6 Hz, 2H), 2.53 (br, 4H), 2.28 (s, 3H), 2.24 (s, 3H), 1.61-1.47 (m, 6H); LC/MS (ESI): 96%.

Provenance & Evidence