Hydrochloric Acid → HCID 46206104, compound

Participants

Reaction Conditions

Reaction Steps

N-(5-{2-[2′-Fluoro-4′-(phenylthio)biphenyl-4-yl]ethyl}-2,2-dimethyl-1,3-dioxan-5-yl)acetamide (468 mg) was dissolved in methanol (6 mL), concentrated hydrochloric acid (3 mL) was added, and the mixture was stirred at 70° C. for 3.5 hr. The reaction mixture was concentrated, and the residual crude crystals were suspended in diisopropyl ether and collected by filtration to give the title compound (329 mg) as white crystals.

Provenance & Evidence