Hydrochloric Acid → HCID 24852497, compound

Participants

Reaction Conditions

Reaction Steps

N-(5-{2-[2′-Fluoro-4′-(4-methoxyphenylthio)biphenyl-4-yl]ethyl}-2,2-dimethyl-1,3-dioxan-5-yl)acetamide (0.22 g) was dissolved in ethanol (4 mL), concentrated hydrochloric acid (2 mL) was added, and the mixture was stirred at 75° C. for 4 hr. The reaction mixture was concentrated to dryness, and the residual solid was suspended in ethyl acetate and collected by filtration to give the title compound (39 mg) as brown crystals.

Provenance & Evidence