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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1641784Generated: November 1, 2026

HCID 57652073, compound → HCID 57652026, compound

https://huagongshe.com/reaction/1641784

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 57652073HCID 57652073—
ReactantHCID 66738250HCID 66738250—
ReactantHCID 66738402HCID 66738402—
ProductHCID 57652026HCID 57652026—

Reaction Steps

With a method similar to that used for the preparation of (S)-3-(5-amino-pyridin-2-ylamino)-pyrrolidine-1-carboxylic acid tert-butyl ester above, (1R,3S)-3-(5-amino-pyridin-2-ylamino)-cyclopentanecarboxylic acid methyl ester was prepared by the hydrogenation of (1R,3S)-3-(5-nitro-pyridin-2-ylamino)-cyclopentanecarboxylic acid methyl ester. This material was directly used in the next step without further purification.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08115011B2
Source datasetuspto-grants-2012_02
ORD IDord-c6511dc442f547b4a4b1e6b96b589a2d
Source noteuspto-grants-2012_02