O-Phenylenediamine → 2-(4-Bromophenyl)-3-phenylquinoxaline

Participants

Reaction Steps

In a 200 mL recovery flask were placed 4.5 g (15 mmol) of 1-(4-bromophenyl)-2-phenylethanedione, 1.8 g (17 mmol) of 1,2-phenylenediamine, and 50 mL of ethanol. This solution was refluxed under nitrogen stream for 2.5 hours. After a predetermined time, the solution was cooled to room temperature, and the precipitated solid was collected by suction filtration. The collected solid was washed with ethanol, so that 5.2 g of target white powder was obtained with a yield of 92%.

Provenance & Evidence