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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 164199Generated: October 30, 2026

Tetrahydrofuran → 1-[4-(4-Chloro-2-fluoro-5-methoxyphenyl)-2-methylpiperazin-1-yl]-2-[3-(1,3-oxazol-2-yl)pyrazolo[5,4-b]pyridin-1-yl]ethanone

https://huagongshe.com/reaction/164199

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTetrahydrofuranHCID 8028—
ReactantEthyl AcetateHCID 8857—
ReactantOxazoleHCID 9255—
ReactantTriphenylphosphineHCID 11776—
ReactantPalladiumHCID 23938—
Reactant1-[4-(4-Chloro-2-fluoro-5-methoxyphenyl)-2-methylpiperazin-1-yl]-2-(3-iodopyrazolo[5,4-b]pyridin-1-yl)ethanoneHCID 16006323—
ReactantButyllithiumHCID 178418339—
Product1-[4-(4-Chloro-2-fluoro-5-methoxyphenyl)-2-methylpiperazin-1-yl]-2-[3-(1,3-oxazol-2-yl)pyrazolo[5,4-b]pyridin-1-yl]ethanoneHCID 16006221—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (9/10)
ORD IDord-5e56ac8481884476b3ac0983edd412d7
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (9/10)