HuagongsheHuagongshe Chemistry Print Report · For research reference only
Diethyl 2-nitrobenzylphosphonate → Diethyl [(2-aminophenyl)methyl]phosphonate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Diethyl 2-nitrobenzylphosphonate | HCID 11277310 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | Diethyl [(2-aminophenyl)methyl]phosphonate | HCID 13649220 | — |
Reaction Steps
1.13 g of (2-nitro-benzyl)-phosphonic acid diethyl ester) in ethanol are hydrogenated with Pd—C as a catalyst for 5 hours at rt and ambient pressure. The catalyst is removed by filtration and from the filtrate obtained solvent is evaporated. (2-Amino-benzyl)-phosphonic acid diethyl ester is obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08119617B2 |
| Source dataset | uspto-grants-2012_02 |
| ORD ID | ord-73e903e834f1447281705517e2b27da9 |
| Source note | uspto-grants-2012_02 |