Water → HCID 66703325, compound

Participants

Reaction Steps

A solution of 4-(morpholin-4-yl-phenylmethyl)cyclohexanone oxime (1.20 g, 4.16 mmol) in absolute tetrahydrofuran (12 ml) was added dropwise at 60° C., under argon, to a suspension of lithium aluminium hydride (316 mg, 8.32 mmol) in absolute tetrahydrofuran (40 ml), and stirring was carried out for 4 h at that temperature. After cooling, water (1.5 ml) and 4 N sodium hydroxide solution (0.4 ml) were added dropwise. The suspension was filtered, and the filtrate was dried over sodium sulfate and concentrated in vacuo.

Provenance & Evidence