HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethylenediamine → Ethyl 2-(3-oxopiperazin-2-yl)acetate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethylenediamine | HCID 3301 | — |
| Reactant | Diethyl Maleate | HCID 5271566 | — |
| Solvent | 1-Propanol | HCID 1031 | — |
| Product | Ethyl 2-(3-oxopiperazin-2-yl)acetate | HCID 544550 | — |
Reaction Steps
Ethylenediamine (1.17 ml, 17.42 mmol) and diethyl maleate (3 g, 17.42 mmol) were stirred for 16 h at 55° C. in propanol (30 ml). The solvent was removed in vacuo and the residue was dried in vacuo. The product was used in the next stage without being purified further.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08119633B2 |
| Source dataset | uspto-grants-2012_02 |
| ORD ID | ord-aa117c5babde45f4804c22ff5604f474 |
| Source note | uspto-grants-2012_02 |