Trifluoroacetic acid → HCID 9855936, compound

HRID 1642199Notes

Reaction equation

HRID 1642199 reaction equation
[CH3:1][O:2][C:3]1[CH:4]=[C:5]([N:9]2[C@H:16]3[C@H:11]([CH2:12][CH2:13][N:14](C(OC(C)(C)C)=O)[CH2:15]3)[CH2:10]2)[CH:6]=[N:7][CH:8]=1.FC(F)(F)C(O)=O>>[CH3:1][O:2][C:3]1[CH:4]=[C:5]([N:9]2[C@H:16]3[C@H:11]([CH2:12][CH2:13][NH:14][CH2:15]3)[CH2:10]2)[CH:6]=[N:7][CH:8]=1

Participants

3

Reactant 2

HCID 6422Trifluoroacetic acidHCID 66757213HCID 66757213, compound

Product 1

HCID 9855936HCID 9855936, compoundYield 91.2%

Procedure

The product of Example 88A (0.540 g, 1.70 mmol) and trifluoroacetic acid were processed according to the procedure described in Example 64C to provide the title compound (0.340 g, 1.55 mmol, 91% yield).

Sources & evidence

ORD record
ord-3a98383f82aa42aca708d12725645ca6
Source dataset
uspto-grants-2012_02
Patent number
US08119635B2

Reaction notes

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