HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 57619809, compound → HCID 55288821, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 57619809 | HCID 57619809 | — |
| Solvent | Hydrochloric Acid | HCID 313 | — |
| Solvent | Methanol | HCID 887 | — |
| Solvent | 1,4-Dioxane | HCID 31275 | — |
| Product | HCID 55288821 | HCID 55288821 | — |
Reaction Steps
A solution tert-butyl N-[(1S,2R)-2-(cyanomethyl)cyclohexyl]carbamate (2 g) in MeOH (40 mL) and 4 M HCl in dioxane (20 mL) was stirred at room temperature for 2 hours and concentrated in vacuo to provide the title compound as a yellow oil, which was used for the subsequent step without further purification.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08119661B2 |
| Source dataset | uspto-grants-2012_02 |
| ORD ID | ord-5d866fdb39624dafadd68d6fe0a7198a |
| Source note | uspto-grants-2012_02 |