Trifluoroacetic acid → HCID 66756492, compound

HRID 1642660Notes

Reaction equation

HRID 1642660 reaction equation
C(OC([NH:8][C@@H:9]([CH2:15][CH2:16][C:17](=O)[CH2:18][CH3:19])[C:10]([O:12][CH2:13][CH3:14])=[O:11])=O)(C)(C)C.FC(F)(F)C(O)=O>ClCCl>[CH2:18]([C:17]1[CH2:16][CH2:15][C@@H:9]([C:10]([O:12][CH2:13][CH3:14])=[O:11])[N:8]=1)[CH3:19]

Participants

4

Reactant 2

HCID 6422Trifluoroacetic acidHCID 86592936HCID 86592936, compound

Product 1

HCID 66756492HCID 66756492, compound

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

Ethyl (2S)-2-((tert-butoxycarbonyl)amino)-5-oxoheptanoate and trifluoroacetic acid (3 mL) were stirred in dichloromethane (3 mL) at room temperature for 3 hours. The mixture was concentrated under reduced pressure to provide the titled compound. MS (ESI) m/z 170 (M+H)+.

Workup

  1. concentrationThe mixture was concentrated under reduced pressure

Sources & evidence

ORD record
ord-e163befb5bc94df99805646fbb7034e7
Source dataset
uspto-grants-2012_02
Patent number
US08119664B2

Reaction notes

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