Hydrochloric Acid → HCID 66755372, compound

HRID 1642802Notes

Reaction equation

HRID 1642802 reaction equation
[CH3:1][O:2][C:3]1[CH:8]=[CH:7][C:6]([CH:9]2[CH2:14][N:13](C(OC(C)(C)C)=O)[CH2:12][CH:11]([C:22]([O:24]CC)=[O:23])[CH2:10]2)=[CH:5][CH:4]=1.[ClH:27]>>[ClH:27].[CH3:1][O:2][C:3]1[CH:8]=[CH:7][C:6]([CH:9]2[CH2:14][NH:13][CH2:12][CH:11]([C:22]([OH:24])=[O:23])[CH2:10]2)=[CH:5][CH:4]=1

Participants

3

Reactant 2

HCID 313Hydrochloric AcidHCID 58002330HCID 58002330, compound

Product 1

HCID 66755372HCID 66755372, compound

Procedure

1.13 g (3.11 mmol) of 1-tert-butyl 3-ethyl 5-(4-methoxyphenyl)piperidine-1,3-dicarboxylate were added to 40 ml of aqueous 1 N hydrochloric acid solution, and the mixture was concentrated on a rotary evaporator. Yield: 829 mg (98% of theory)

Workup

  1. concentrationthe mixture was concentrated on a rotary evaporator

Sources & evidence

ORD record
ord-4563b015ba0244f685e9b95b822e0f8d
Source dataset
uspto-grants-2012_02
Patent number
US08119663B2

Reaction notes

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