HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Methylpropanehydrazide → N'-(2-Methylpropanoyl)-1-(morpholin-4-ylcarbonyl)-5-[4-(trifluoromethoxy)phenyl]piperidine-3-carbohydrazide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Methylpropanehydrazide | HCID 19239 | — |
| Reactant | 1-(Morpholin-4-ylcarbonyl)-5-[4-(trifluoromethoxy)phenyl]piperidine-3-carboxylic acid | HCID 58002500 | — |
| Product | N'-(2-Methylpropanoyl)-1-(morpholin-4-ylcarbonyl)-5-[4-(trifluoromethoxy)phenyl]piperidine-3-carbohydrazide | HCID 58002287 | — |
Reaction Steps
100 mg (0.25 mmol) of the compound from Example 44A and 51 mg (0.50 mmol) of 2-methylpropanehydrazide were reacted according to the General Method 11A. Yield: 80 mg (66% of theory)
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08119663B2 |
| Source dataset | uspto-grants-2012_02 |
| ORD ID | ord-10950c2147b443728d816cce310234d6 |
| Source note | uspto-grants-2012_02 |