HuagongsheHuagongshe Chemistry Print Report · For research reference only
N'-hydroxy-2-propan-2-ylsulfonylethanimidamide → [3-(3,4-Dimethylphenyl)-5-[3-[(propan-2-ylsulphonyl)methyl]-1,2,4-oxadiazol-5-yl]piperidin-1-yl](morpholin-4-yl)methanone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | N'-hydroxy-2-propan-2-ylsulfonylethanimidamide | HCID 2819602 | — |
| Reactant | HCID 58002579 | HCID 58002579 | — |
| Product | [3-(3,4-Dimethylphenyl)-5-[3-[(propan-2-ylsulphonyl)methyl]-1,2,4-oxadiazol-5-yl]piperidin-1-yl](morpholin-4-yl)methanone | HCID 58002219 | — |
Reaction Steps
100 mg (0.289 mmol) of the compound from Example 130A and 78 mg (0.433 mmol) of N′-hydroxy-2-(propan-2-ylsulphonyl)ethanimidamide were reacted according to the General Method 2. Yield: 108 mg (75% of theory)
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08119663B2 |
| Source dataset | uspto-grants-2012_02 |
| ORD ID | ord-9f9a78aa53444130b21f96f46f7dbfaa |
| Source note | uspto-grants-2012_02 |