HuagongsheHuagongshe Chemistry Print Report · For research reference only
N-Hydroxyacetamidine → [3-(3,4-Dimethylphenyl)-5-(3-methyl-1,2,4-oxadiazol-5-yl)piperidin-1-yl] (morpholin-4-yl)-methanone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | N-Hydroxyacetamidine | HCID 30926 | — |
| Reactant | HCID 58002579 | HCID 58002579 | — |
| Product | [3-(3,4-Dimethylphenyl)-5-(3-methyl-1,2,4-oxadiazol-5-yl)piperidin-1-yl] (morpholin-4-yl)-methanone | HCID 58002237 | — |
Reaction Steps
100 mg (0.29 mmol) of the compound from Example 130A and 33 mg (0.43 mmol) of N′-hydroxyacetamidine were reacted according to the General Method 2. Yield: 68 mg (61% of theory)
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08119663B2 |
| Source dataset | uspto-grants-2012_02 |
| ORD ID | ord-0ea2c94d6af54a60a0f26a4dd7b9b9a8 |
| Source note | uspto-grants-2012_02 |