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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1643023Generated: November 1, 2026

N-Hydroxyacetamidine → HCID 58002560, compound

https://huagongshe.com/reaction/1643023

Reaction equation

Participants

RoleNameHCIDCharge
ReactantN-HydroxyacetamidineHCID 30926—
Reactant1-(Morpholin-4-ylcarbonyl)-5-[4-(trifluoromethoxy)phenyl]piperidine-3-carboxylic acidHCID 58002500—
ProductHCID 58002560HCID 58002560—

Reaction Steps

200 mg (0.50 mmol) of the compound from Example 44A and 74 mg (0.75 mmol) of N′-hydroxyethanimidamide were reacted according to the General Method 2. Yield: 119 mg (52% of theory)

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08119663B2
Source datasetuspto-grants-2012_02
ORD IDord-ba496614a06749a2aed98c8f423df73f
Source noteuspto-grants-2012_02