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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1643074Generated: November 1, 2026

N-Hydroxynicotinimidamide → HCID 58002615, compound

https://huagongshe.com/reaction/1643074

Reaction equation

Participants

RoleNameHCIDCharge
ReactantN-HydroxynicotinimidamideHCID 308113—
Reactant1-[(3-Hydroxyazetidin-1-yl)carbonyl]-5-[4-(trifluoromethyl)phenyl]piperidine-3-carboxylic acidHCID 58002578—
ProductHCID 58002615HCID 58002615—

Reaction Steps

100 mg (0.269 mmol) of 1-[(3-hydroxyazetidin-1-yl)carbonyl]-5-[4-(trifluoromethyl)phenyl]piperidine-3-carboxylic acid (Example 101A) and 40.5 mg (0.295 mmol) of N′-hydroxypyridine-3-carboximidamide were reacted according to the General Method 1. Yield: 28.8 mg (21% of theory).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08119663B2
Source datasetuspto-grants-2012_02
ORD IDord-439e1bd7df754a8cb059eeb06e2bf2f6
Source noteuspto-grants-2012_02