Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1643119Generated: November 3, 2026

N-Hydroxyacetamidine → HCID 58002452, compound

https://huagongshe.com/reaction/1643119

Reaction equation

Participants

RoleNameHCIDCharge
ReactantN-HydroxyacetamidineHCID 30926—
Reactant1-[(4-Hydroxypiperidin-1-yl)carbonyl]-5-[4-(trifluoromethoxy)phenyl]piperidine-3-carboxylic acidHCID 58002415—
ProductHCID 58002452HCID 58002452—

Reaction Steps

200 mg (0.480 mmol) of the compound from Example 63A and 71 mg (0.961 mmol) of N′-hydroxyethanimidamide were reacted according to the General Method 2. Yield: 144 mg (62% of theory)

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08119663B2
Source datasetuspto-grants-2012_02
ORD IDord-2c27e9e518864f9a9c2e9a3b1e5f4f1a
Source noteuspto-grants-2012_02