HRID1643145

反应详情

EQUATION

反应方程式

REACTANTS

反应物

结构：COc1ccc(P2(=S)SP(=S)(c3ccc(OC)cc3)S2)cc1

HCID87949

p-Anisyldithiophosphonic anhydride

C14H14O2P2S4

结构：O=C(NNC(=O)C1CC(c2ccc(OC(F)(F)F)cc2)CN(C(=O)N2CCOCC2)C1)c1ccccc1

HCID58002666

未命名化合物

PRODUCTS

生成物

结构：O=C(N1CCOCC1)N1CC(c2ccc(OC(F)(F)F)cc2)CC(c2nnc(-c3ccccc3)s2)C1

HCID58002639

未命名化合物

PROCEDURE

实验过程

132 mg (0.239 mmol) of the compound from Example 123A and 193 mg (0.478 mmol) of Lawesson reagent were reacted according to the General Method 9. Yield: 40 mg (32% of theory)

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-a3e1c2c8058847bd9faaa78e962c6ab9
来源数据集: uspto-grants-2012_02
DOI: 10.6084/m9.figshare.5104873.v1
专利: US08119663B2
来源说明: uspto-grants-2012_02

反应 SMILES

[N:1]1([C:7]([N:9]2[CH2:14][CH:13]([C:15]3[CH:20]=[CH:19][C:18]([O:21][C:22]([F:25])([F:24])[F:23])=[CH:17][CH:16]=3)[CH2:12][CH:11]([C:26]([NH:28][NH:29][C:30]([C:32]3[CH:37]=[CH:36][CH:35]=[CH:34][CH:33]=3)=O)=O)[CH2:10]2)=[O:8])[CH2:6][CH2:5][O:4][CH2:3][CH2:2]1.COC1C=CC(P2(SP(C3C=CC(OC)=CC=3)(=S)S2)=[S:47])=CC=1>>[N:1]1([C:7]([N:9]2[CH2:14][CH:13]([C:15]3[CH:20]=[CH:19][C:18]([O:21][C:22]([F:25])([F:24])[F:23])=[CH:17][CH:16]=3)[CH2:12][CH:11]([C:26]3[S:47][C:30]([C:32]4[CH:37]=[CH:36][CH:35]=[CH:34][CH:33]=4)=[N:29][N:28]=3)[CH2:10]2)=[O:8])[CH2:6][CH2:5][O:4][CH2:3][CH2:2]1