Water → tert-butyl N-[3-(fluoromethoxy)-6,7,8,9-tetrahydro-5H-benzo[7]annulen-6-yl]-N-(2-hydroxy-3-phenoxypropyl)carbamate

HRID 164316Notes

Reaction equation

HRID 164316 reaction equation
[CH2:42]([N+:43]([CH2:44][CH2:45][CH2:46][CH3:47])([CH2:48][CH2:49][CH2:50][CH3:51])[CH2:52][CH2:53][CH2:54][CH3:55])[CH2:56][CH2:57][CH3:58].[F-:41].[F:1][CH2:2][O:3][c:4]1[cH:5][c:6]2[c:7]([cH:39][cH:40]1)[CH2:8][CH2:9][CH2:10][CH:11]([N:13]([C:14](=[O:15])[O:16][C:17]([CH3:18])([CH3:19])[CH3:20])[CH2:21][CH:22]([CH2:23][O:24][c:25]1[cH:26][cH:27][cH:28][cH:29][cH:30]1)[O:31][Si:32]([CH2:33][CH3:34])([CH2:35][CH3:36])[CH2:37][CH3:38])[CH2:12]2.[O:60]1[CH2:61][CH2:62][CH2:63][CH2:64]1.[OH2:59]>>[F:1][CH2:2][O:3][c:4]1[cH:5][c:6]2[c:7]([cH:39][cH:40]1)[CH2:8][CH2:9][CH2:10][CH:11]([N:13]([C:14](=[O:15])[O:16][C:17]([CH3:18])([CH3:19])[CH3:20])[CH2:21][CH:22]([CH2:23][O:24][c:25]1[cH:26][cH:27][cH:28][cH:29][cH:30]1)[OH:31])[CH2:12]2

Participants

6

Reactant 5

HCID 962WaterHCID 8028TetrahydrofuranHCID 16028TetrabutylammoniumHCID 28179Fluoride IonHCID 178477592HCID 178477592, compound

Product 1

HCID 178453770tert-butyl N-[3-(fluoromethoxy)-6,7,8,9-tetrahydro-5H-benzo[7]annulen-6-yl]-N-(2-hydroxy-3-phenoxypropyl)carbamate

Sources & evidence

ORD record
ord-3c0c2be8b74d46daa0fa35597c642a6a
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Reaction notes

Loading…