Hydrochloric Acid → HCID 86639747, compound

HRID 1643239Notes

Reaction equation

HRID 1643239 reaction equation
[C:1]([C:5]1[CH:10]=[C:9]([SH:11])[CH:8]=[C:7]([C:12]([CH3:15])([CH3:14])[CH3:13])[C:6]=1[OH:16])([CH3:4])([CH3:3])[CH3:2].[C:17]1(=O)[CH2:23][CH2:22][CH2:21][CH2:20][CH2:19][CH2:18]1.Cl>CO>[C:1]([C:5]1[CH:10]=[C:9]([S:11][C:17]2([S:11][C:9]3[CH:8]=[C:7]([C:12]([CH3:13])([CH3:14])[CH3:15])[C:6]([OH:16])=[C:5]([C:1]([CH3:4])([CH3:3])[CH3:2])[CH:10]=3)[CH2:23][CH2:22][CH2:21][CH2:20][CH2:19][CH2:18]2)[CH:8]=[C:7]([C:12]([CH3:15])([CH3:14])[CH3:13])[C:6]=1[OH:16])([CH3:4])([CH3:3])[CH3:2]

Participants

5

Reactant 3

HCID 313Hydrochloric AcidHCID 10400CycloheptanoneHCID 703702,6-Di-tert-butyl-4-mercaptophenol

Product 1

HCID 86639747HCID 86639747, compoundYield 76.2%

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

To a solution of 2,6-di-t-butyl-4-mercaptophenol (3.00 g, 12.6 mmol) in methanol (10 mL) was added cycloheptanone (1.63 mL, 13.8 mmol) and a catalytic amount of concentrated hydrochloric acid. The mixture was stirred at a room temperature overnight. The generated precipitate was separated by a filtration and dried to give objective bis(3,5-di-t-butyl-4-hydroxyphenylthio)cycloheptane (yield 2.74 g and 76%).

Workup

  1. customThe generated precipitate was separated by a filtration
  2. customdried

Sources & evidence

ORD record
ord-a19d2fa3913c4bfb836d4af9770427c6
Source dataset
uspto-grants-2012_02
Patent number
US08119686B2

Reaction notes

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