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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1643294Generated: October 31, 2026

Trifluoroacetic acid → HCID 59568786, compound

https://huagongshe.com/reaction/1643294

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTrifluoroacetic acidHCID 6422—
ReactantHCID 59568806HCID 59568806—
SolventDichloromethaneHCID 6344—
ProductHCID 59568786HCID 59568786—

Reaction Conditions

Temperature25 °C

Reaction Steps

To a solution of tert-butyl 4-((3S,5R)-5-(4-fluorophenyl)-5-methoxy-3-(methoxycarbonyl)pentyl)piperazine-1-carboxylate in 200 μL DCM was slowly added 2 mL TFA and the resulting solution stirred for 30 min at 25° C. The solvent was evaporated under reduced pressure and the crude product was used directly in the next reaction without further purification.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08119692B2
Source datasetuspto-grants-2012_02
ORD IDord-1fe13399ed514420a0eab174696ecc84
Source noteuspto-grants-2012_02