HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1643294Generated: October 31, 2026
Trifluoroacetic acid → HCID 59568786, compound
https://huagongshe.com/reaction/1643294
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Trifluoroacetic acid | HCID 6422 | — |
| Reactant | HCID 59568806 | HCID 59568806 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 59568786 | HCID 59568786 | — |
Reaction Steps
To a solution of tert-butyl 4-((3S,5R)-5-(4-fluorophenyl)-5-methoxy-3-(methoxycarbonyl)pentyl)piperazine-1-carboxylate in 200 μL DCM was slowly added 2 mL TFA and the resulting solution stirred for 30 min at 25° C. The solvent was evaporated under reduced pressure and the crude product was used directly in the next reaction without further purification.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US08119692B2 |
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| Source dataset | uspto-grants-2012_02 |
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| ORD ID | ord-1fe13399ed514420a0eab174696ecc84 |
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| Source note | uspto-grants-2012_02 |
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