HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1643450Generated: November 1, 2026
Trifluoroacetic acid → HCID 59367776, compound
https://huagongshe.com/reaction/1643450
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Trifluoroacetic acid | HCID 6422 | — |
| Reactant | HCID 67356290 | HCID 67356290 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 59367776 | HCID 59367776 | — |
Reaction Steps
tert-Butyl 9-(pyridin-3-yl)-9-(2-(pyrrolidin-1-yl)ethoxy)-3-azaspiro[5.5]undecane-3-carboxylate (0.33 mmol, 1 eq) was dissolved in methylene chloride (3.5 ml). TFA (0.7 ml) was added at 0° C. and the mixture was stirred at 25° C. for 1 h. The solvent was concentrated to dryness under reduced pressure and the resulting desired product was employed in the next stage without further purification.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US08119805B2 |
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| Source dataset | uspto-grants-2012_02 |
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| ORD ID | ord-483bedf81f934c979dc25971a995b68a |
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| Source note | uspto-grants-2012_02 |
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