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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1643450Generated: November 1, 2026

Trifluoroacetic acid → HCID 59367776, compound

https://huagongshe.com/reaction/1643450

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTrifluoroacetic acidHCID 6422—
ReactantHCID 67356290HCID 67356290—
SolventDichloromethaneHCID 6344—
ProductHCID 59367776HCID 59367776—

Reaction Conditions

Temperature25 °C

Reaction Steps

tert-Butyl 9-(pyridin-3-yl)-9-(2-(pyrrolidin-1-yl)ethoxy)-3-azaspiro[5.5]undecane-3-carboxylate (0.33 mmol, 1 eq) was dissolved in methylene chloride (3.5 ml). TFA (0.7 ml) was added at 0° C. and the mixture was stirred at 25° C. for 1 h. The solvent was concentrated to dryness under reduced pressure and the resulting desired product was employed in the next stage without further purification.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08119805B2
Source datasetuspto-grants-2012_02
ORD IDord-483bedf81f934c979dc25971a995b68a
Source noteuspto-grants-2012_02