反应详情

(1-(3-(Trifluoromethyl)phenylsulfonyl)piperidin-2-yl)methanesulfonic acid was dissolved in benzene (3 ml), thionyl chloride (0.034 ml) was added and the mixture was refluxed for 4 h. After cooling, the reaction mixture was concentrated in vacuo and the crude product was employed in the next stage without purification.

1. temperaturethe mixture was refluxed for 4 h
2. temperatureAfter cooling
3. concentrationthe reaction mixture was concentrated in vacuo
4. customthe crude product was employed in the next stage without purification