Phenylboronic Acid → N-(6-phenyl-1,2,3,4-tetrahydroquinolin-3-yl)benzenesulfonamide

HRID 1643904Notes

Reaction equation

HRID 1643904 reaction equation
Br[C:2]1[CH:3]=[C:4]2[C:9](=[CH:10][CH:11]=1)[NH:8][CH2:7][CH:6]([NH:12][S:13]([C:16]1[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=1)(=[O:15])=[O:14])[CH2:5]2.[C:22]1(B(O)O)[CH:27]=[CH:26][CH:25]=[CH:24][CH:23]=1>>[C:22]1([C:2]2[CH:3]=[C:4]3[C:9](=[CH:10][CH:11]=2)[NH:8][CH2:7][CH:6]([NH:12][S:13]([C:16]2[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=2)(=[O:15])=[O:14])[CH2:5]3)[CH:27]=[CH:26][CH:25]=[CH:24][CH:23]=1

Participants

3

Reactant 2

HCID 66827Phenylboronic AcidHCID 18177113N-(6-Bromo-1,2,3,4-tetrahydroquinolin-3-yl)-benzenesulfonamide

Product 1

HCID 17758907N-(6-phenyl-1,2,3,4-tetrahydroquinolin-3-yl)benzenesulfonamide

Procedure

Compound 170A was prepared from 87A and phenylboronic acid by procedures analogous to those described in Example 91A.

Sources & evidence

ORD record
ord-e609acf8a9f54153804ea4129ce7377d
Source dataset
uspto-grants-2012_02
Patent number
US08119808B2

Reaction notes

Loading…