反应详情

1.00 g (3.08 mmol) of tert-butyl (2-oxo-2,3-dihydrobenzimidazol-1-yl)acetate (XId) was dissolved in dichloromethane (10 ml) and, while stirring at room temperature, trifluoroacetic acid (6 ml) was added. The reaction solution was stirred for 2 h and then the solvent and excess trifluoroacetic acid were removed in vacuo. The residue was taken up again in toluene, concentrated in vacuo and then dried in vacuo. Yield: 827 mg (100%) of white solid

1. stirringThe reaction solution was stirred for 2 h
2. customthe solvent and excess trifluoroacetic acid were removed in vacuo
3. concentrationconcentrated in vacuo
4. customdried in vacuo